Title | Authors | Journal | Date | Link |
Implications and prognostic impact of mass spectrometry in patients with newly-diagnosed multiple myeloma | Mai EK et al. | Blood Cancer J. | 4 January 2023 | |
C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells | de Laval B et al. | Cell Stem Cell. | 5 January 2023 | |
Alterations of cohesin complex genes in acute myeloid leukemia: differential co-mutations, clinical presentation and impact on outcome | Eckardt JN et al. | Blood Cancer J. | 24 January 2023 | |
Anti-SARS-CoV-2 antibody-containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19: a randomized clinical trial | Denkinger CM et al. | Nat Cancer. | January 2023 | |
All-trans retinoic acid works synergistically with the γ-secretase inhibitor crenigacestat to augment BCMA on multiple myeloma and the efficacy of BCMA-CAR T cells | García-Guerrero E et al. | Haematologica. | 1 February 2023 | |
Engineering CD20 CARs with a Twist | Scheller L et al . | Cancer Immunol Res. | 3 February 2023 | |
Palbociclib impairs the proliferative capacity of activated T cells while retaining their cytotoxic efficacy | Arndt C et al. | Front Pharmacol. | 3 February 2023 | |
A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia | Zhou F et al . | Cancer Discov. | 6 February 2023 | |
Medical microrobots in reproductive medicine from the bench to the clinic | Nauber R et al. | Nat Commun. | 9 February 2023 | |
Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes | Gainullina A et al. | Cell Rep. | 28 February 2023 | |
Non-viral TRAC-knocked-in CD19KICAR-T and gp350KICAR-T cells tested against Burkitt lymphomas with type 1 or 2 EBV infection: In vivo cellular dynamics and potency | Braun T et al. | Front Immunol. | 24 March 2023 | |
Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in SF3B1-mutated myelodysplasia | Mian SA et al. | Sci Transl Med. | March 2023 | |
Allogeneic Hematopoietic Cell Transplantation vs Standard Consolidation Chemotherapy in Patients With Intermediate-Risk Acute Myeloid Leukemia: A Randomized Clinical Trial | Bornhäuser M et al. | JAMA Oncol. | 1 April 2023 | |
Specific and safe targeting of glioblastoma using switchable and logic-gated RevCAR T cells | Saleh HA et al. | Front Immunol. | 14 April 2023 | |
Consensus proposal for revised International Working Group 2023 response criteria for higher-risk myelodysplastic syndromes | Zeidan AM et al. | Blood. | 27 April 2023 | |
Risk prediction in MDS: independent validation of the IPSS-M-ready for routine? | Baer C et al. | Leukemia. | April 2023 | |
Prognostic impact of the post-treatment T cell composition and spatial organization in soft tissue sarcoma patients treated with neoadjuvant hyperthermic radio(chemo)therapy | Rupp L et al. | Front Immunol. | 16 May 2023 | |
UBTF tandem duplications are rare but recurrent alterations in adult AML and associated with younger age, myelodysplasia, and inferior outcome | Georgi JA et al. | Blood Cancer J. | 26 May 2023 | |
Novel evidence that the ABO blood group shapes erythropoiesis and results in higher hematocrit for blood group B carriers | Kronstein-Wiedemann R et al. | Leukemia. | May 2023 | |
Specific and safe targeting of glioblastoma using switchable and logic-gated RevCAR T cells | Chihara D et al. | Haematologica. | 1 June 2023 | |
A novel ACE2 decoy for both neutralization of SARS-CoV-2 variants and killing of infected cells | Kegler A et al. | Front Immunol. | 13 June 2023 | |
CRISPR/Cas9 Screen in Gastric Cancer Patient-Derived Organoids Reveals KDM1A-NDRG1 Axis as a Targetable Vulnerability | Mircetic J et al. | Small Methods. | June 2023 | |
Precise excision of HTLV-1 provirus with a designer-recombinase | Rojo-Romanos T et al. | Mol Ther. | 5 July 2023 | |
Efficacy and safety of luspatercept versus epoetin alfa in erythropoiesis-stimulating agent-naive, transfusion-dependent, lower-risk myelodysplastic syndromes (COMMANDS): interim analysis of a phase 3, open-label, randomised controlled trial | Platzbecker U et al. | Lancet. | July 2023 | |
Impact of trisomy 19 on outcome according to genetic makeup in patients with acute myeloid leukemia | Kayser S et al. | Haematologica. | 1 August 2023 | |
Teclistamab impairs detection of BCMA CAR-T cells | Glatte B et al. | Blood Adv. | 8 August 2023 | |
ErbB2 (HER2)-CAR-NK-92 cells for enhanced immunotherapy of metastatic fusion-driven alveolar rhabdomyosarcoma | Heim C et al. | Front Immunol. | 18 August 2023 | |
Editorial: Translating NK cell scientific research to clinical product manufacturing | Ullrich E et al. | Front Immunol. | August 2023 | |
Midostaurin in addition to intensive chemotherapy in acute myeloid leukemia with t(8;21) and KIT and/or FLT3- ITD mutations: results of the SAL MIDOKIT trial | Ruhnke L et al. | Haematologica. | 1 September 2023 | |
Graft- versus-host disease and relapse/rejection-free survival after allogeneic transplantation for idiopathic severe aplastic anemia: a comprehensive analysis from the SAAWP of the EBMT | Devillier R et al. | Haematologica. | 1 September 2023 | |
Engineering NK-CAR.19 cells with the IL-15/IL-15Rα complex improved proliferation and anti-tumor effect in vivo | Silvestre RN et al. | Front. Immunol. | 25 September 2023 | |
Learning from the microbes: exploiting the microbiome to enforce T cell immunotherapy | Staudt S et al. | Front. Immunol. | September 2023 | |
FLT3-directed UniCAR T-cell therapy of acute myeloid leukaemia | Peschke JC et al. | Br J Haematol. | September 2023 | |
Preclinical assessment of CAR-NK cell-mediated killing efficacy and pharmacokinetics in a rapid zebrafish xenograft model of metastatic breast cancer | Shankar NM et al. | Front. Immunol. | 11 October 2023 | |
CAR-Ts redirected against the Thomsen-Friedenreich antigen CD176 mediate specific elimination of malignant cells from leukemia and solid tumors | Dragon AC et al. | Front. Immunol. | 17 October 2023 | |
Quantification of evolved DNA-editing enzymes at scale with DEQSeq | Schmitt LT et al. | Genome Biol. | 6 November 2023 | |
M-CSF directs myeloid and NK cell differentiation to protect from CMV after hematopoietic cell transplantation | Kandalla PK et al. | EMBO Mol Med. | 8 November 2023 | |
Ruscher C, Patzina-Mehling C, Melchert J, Graff SL, McFarland SE, Hieke C, Kopp A, Prasser A, Tonn T, Schmidt M, Isner C, Drosten C, Werber D, Corman VM, Junglen S | Emde-Rajaratnam M et al. | Front Immunol. | 15 November 2023 | |
Immune Surveillance of Acute Myeloid Leukemia Is Mediated by HLA-Presented Antigens on Leukemia Progenitor Cells | Nelde A et al. | Blood Cancer Discov. | 1 November 2023 | |
CD44v6 specific CAR-NK cells for targeted immunotherapy of head and neck squamous cell carcinoma | Ciulean OS et al. | Front Immunol. | 10 November 2023 | |
Accelerating development of engineered T cell therapies in the EU: current regulatory framework for studying multiple product versions and T2EVOLVE recommendations | Ammar D et al. | Front Immunol. | 24 November 2023 | |
Ecological and clinical evidence of the establishment of West Nile virus in a large urban area in Europe, Berlin, Germany, 2021 to 2022 | Ruscher C et al. | Euro Surveill. | November 2023 | |
Ex vivo drug response profiling for response and outcome prediction in hematologic malignancies: the prospective non-interventional SMARTrial | Liebers N et al. | Nat Cancer. | 4 December 2023 | |
Immunotheranostic target modules for imaging and navigation of UniCAR T-cells to strike FAP-expressing cells and the tumor microenvironment | Loureiro LR et al. | J Exp Clin Cancer Res. | 15 December 2023 | |
Targeting colorectal cancer cells using AND-gated adaptor RevCAR T-cells | Front Immunol. | Front Immunol. | 15 December 2023 | |
Mutated IKZF1 is an independent marker of adverse risk in acute myeloid leukemia | Eckardt JN et al. | Leukemia. | December 2023 |
What lies behind SaxoCell’s research and development projects? What are the scientists working on, and what new treatment options could emerge from their work? Six new short videos offer exciting insights into the cluster’s current translational projects.
